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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTTN
All Species:
12.42
Human Site:
Y421
Identified Species:
24.85
UniProt:
Q14247
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14247
NP_005222.2
550
61586
Y421
R
L
P
S
S
P
V
Y
E
D
A
A
S
F
K
Chimpanzee
Pan troglodytes
XP_508613
542
59878
Y413
R
L
P
S
S
P
I
Y
E
D
A
A
S
F
K
Rhesus Macaque
Macaca mulatta
XP_001100193
550
61624
Y421
R
L
P
S
S
P
V
Y
E
D
A
A
S
F
K
Dog
Lupus familis
XP_851317
541
60553
P412
P
A
S
P
T
P
Q
P
A
Q
E
K
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q60598
546
61241
S417
P
I
E
D
R
P
P
S
S
P
I
Y
E
D
A
Rat
Rattus norvegicus
Q9JHL4
436
48594
S311
S
Y
G
R
E
P
T
S
P
V
S
R
P
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507265
462
52591
S337
E
D
A
T
P
Y
K
S
D
P
T
R
Q
S
P
Chicken
Gallus gallus
Q01406
563
63311
V434
S
P
V
Y
Q
D
A
V
S
Y
D
A
E
S
A
Frog
Xenopus laevis
Q6GM14
376
42749
R251
Q
T
V
P
A
S
Q
R
S
V
N
P
R
E
M
Zebra Danio
Brachydanio rerio
NP_001004121
504
56595
K378
E
R
S
R
R
Q
A
K
E
K
Q
E
Q
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU84
531
58711
S401
S
P
H
S
K
S
N
S
L
Q
S
Q
S
P
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999782
587
64904
T456
E
P
N
L
Y
E
D
T
G
D
V
G
T
N
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
98.3
90.5
N.A.
92.1
23.8
N.A.
64.9
83.4
26.7
68
N.A.
21.4
N.A.
N.A.
46.5
Protein Similarity:
100
91
99
94.1
N.A.
95
40.1
N.A.
74.1
90
41.2
80
N.A.
38
N.A.
N.A.
59.8
P-Site Identity:
100
93.3
100
6.6
N.A.
6.6
6.6
N.A.
0
6.6
0
6.6
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
13.3
N.A.
13.3
6.6
13.3
13.3
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
9
0
17
0
9
0
25
34
0
9
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
0
9
9
0
9
34
9
0
0
9
9
% D
% Glu:
25
0
9
0
9
9
0
0
34
0
9
9
17
17
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
9
% F
% Gly:
0
0
9
0
0
0
0
0
9
0
0
9
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
9
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
9
0
9
9
0
9
0
9
0
0
25
% K
% Leu:
0
25
0
9
0
0
0
0
9
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
9
0
0
0
9
0
0
0
9
0
0
9
0
% N
% Pro:
17
25
25
17
9
50
9
9
9
17
0
9
17
17
17
% P
% Gln:
9
0
0
0
9
9
17
0
0
17
9
9
17
0
0
% Q
% Arg:
25
9
0
17
17
0
0
9
0
0
0
17
9
0
0
% R
% Ser:
25
0
17
34
25
17
0
34
25
0
17
0
34
17
0
% S
% Thr:
0
9
0
9
9
0
9
9
0
0
9
0
9
0
0
% T
% Val:
0
0
17
0
0
0
17
9
0
17
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
9
9
9
0
25
0
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _